3. Early Cancer in the Large Intestine

Large Intestine

The equine large intestine consists of the following segments (in aboral direction): the cecum, the large colon, and the small colon (Fig. 36-1). Although these segments form a continuum for the passage of digesta from the ileum to the anus, the three portions are considered to be separate structures, anatomically, functionally, and surgically. The large intestine of the horse is well developed...

Disorders of the Large Intestine

Irritable bowel syndrome (IBS) is a chronic non–life-threatening disorder characterized by abdominal pain and alteration in bowel habits. IBS is an extremely common disorder; estimates put the prevalence in the North American population at 10 to 15%, with women affected twice as often as men. Although only one third of patients who have the clinical syndrome ever seek medical attention, IBS acc...

Absorption and Secretion in the Large Intestine.

Protein Degradation in the Large Intestine:

Colorectal cancer is the second most common form of cancer death in Western countries. Diet has been implicated in the aetiology of this disease. Epidemiological evidence suggests that diets high in meat and fat and low in fermentable carbohydrate increase colorectal cancer risk. One mechanism that could explain the association with meat is increased colonic protein metabolism due to increased ...

Ammonia in the large intestine of herbivores.

I. The object was to investigate the importance of urea as a source of ammonia in the large intestine of herbivores. Urea was present in small intestinal contents of slaughtered horses in concentrations similar to those in blood but, in the small intestine of slaughtered sheep, the urea was less than in blood. 2. There was little ammonia in small intestinal contents of slaughtered horses but co...